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Simvotin EZ (Simvastatin + Ezetemibe)
SELECT REF DESCRIPTION MANUFACTURER PACK SIZE STRENGTH OUR PRICE
P1212 Simvotin EZ (Simvastatin + Ezetemibe) Ranbaxy 10 tabs 10 mg+10 mg $8.41
P1207 Simcard (simvastatin) Cipla 10 tabs 5 mg $4.80
P1208 Simcard (simvastatin) Cipla 10 tabs 10 mg $6.88
P1209 Simcard (simvastatin) Cipla 10 tabs 20 mg $12.02
J547 Simvastatin Generic 10 tabs 10 mg $2.80
J548 Simvastatin Generic 10 tabs 20 mg $3.60
J315 Zocor (Simvastatin) Generic 10 tabs 10 mg $6.34
J316 Zocor (Simvastatin) Generic 10 tabs 20 mg $13.41
P1221 Simvotin EZ 20 (Simvastatin + Ezetemibe) Ranbaxy 10 tabs 20 mg+10 mg $16.47
Price is per pack & not per tab.. eg: if pack size is 10 tabs & price is $2.75 then for 100 tabs the price would be $27.50
What is simvastatin?
Simvastatin is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body.

Simvastatin reduces low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood. Lowering your cholesterol can help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease.

Simvastatin may also be used for other purposes not listed in this medication guide.

Important information about simvastatin
In rare cases, simvastatin can cause a condition that results in the breakdown of skeletal muscle tissue. This condition can lead to kidney failure. Call your doctor at once if you have unexplained muscle pain or tenderness, muscle weakness, fever or flu symptoms, and dark colored urine.

Simvastatin can cause birth defects in an unborn baby. Do not use if you are pregnant. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment. Do not take simvastatin if you have liver disease or if you are breast-feeding.

Before taking this medicine, tell your doctor if you have diabetes, underactive thyroid, kidney disease, a muscle disorder, or a blood disorder:

Avoid eating foods that are high in fat or cholesterol. Simvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Avoid drinking alcohol while taking simvastatin. Alcohol can raise triglyceride levels, and may also damage your liver while you are taking this medicine.

There are many other drugs that can interact with simvastatin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Before taking simvastatin
Do not use this medication if you are allergic to simvastatin, if you are pregnant or breast-feeding, or if you have liver disease.

Before taking simvastatin, tell your doctor if you are allergic to any drugs, or if you have:

diabetes;

underactive thyroid;

kidney disease; or

a muscle disorder.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take simvastatin.

FDA pregnancy category X. Simvastatin can cause birth defects. Do not use this medication if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. It is not known whether simvastatin passes into breast milk. Do not take this medication without telling your doctor if you are breast-feeding a baby. Simvastatin is not for use in children younger than 10 years of age.

How should I take simvastatin?
Take simvastatin exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take simvastatin with a full glass of water. Simvastatin is usually taken at bedtime or with an evening meal. If you take this medicine several times daily, take it with meals. Follow your doctor's instructions.

To be sure simvastatin is helping your condition, your blood will need to be tested on a regular basis. Your liver function may also need to be tested. Do not miss any scheduled appointments.

In rare cases, this medicine can cause a condition that results in the breakdown of skeletal muscle tissue. This condition can lead to kidney failure. Call your doctor at once if you have unexplained muscle pain or tenderness, muscle weakness, fever or flu symptoms, and dark colored urine.

Simvastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

You may need to take simvastatin on a long-term basis for the treatment of high cholesterol.

Store this medicine at room temperature, protected from moisture, heat, and light.

What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of simvastatin is not expected to produce life-threatening symptoms.

What should I avoid while taking simvastatin?
Avoid eating foods that are high in fat or cholesterol. Simvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Avoid drinking alcohol while taking this medicine. Alcohol can raise triglyceride levels, and may also damage your liver while you are taking simvastatin.

Grapefruit and grapefruit juice may interact with simvastatin and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

Simvastatin side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using simvastatin and call your doctor at once if you have any of these serious side effects:

muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine.

Less serious simvastatin side effects may include:

mild stomach pain, gas, bloating, stomach upset, heartburn;

nausea;

constipation; or

diarrhea.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

Simvastatin Dosing Information
Usual Adult Dose for Hyperlipidemia:

Initial dose: 5 to 10 mg once a day in the evening.
Maintenance dose: 5 to 80 mg once a day in the evening.

Usual Pediatric Dose for Heterozygous Familial Hypercholesterolemia:

10 to 17 years:
Initial dose: 10 mg once a day in the evening.
Maintenance dose: 10 to 40 mg/day (the maximum recommended dose is 40 mg/day).

What other drugs will affect simvastatin?
Many drugs can interact with simvastatin. Below is just a partial list. Tell your doctor if you are using:

danazol (Danocrine);

gemfibrozil (Lopid), clofibrate (Atromid-S), or fenofibrate (Tricor);

niacin (Nicolar, Nicobid, Slo-Niacin, others);

nefazodone (Serzone);

cholestyramine (Questran) or colestipol (Colestid);

warfarin (Coumadin);

amiodarone (Cordarone), diltiazem (Cartia, Cardizem, Dilacor, Tiazac), or verapamil (Verelan, Calan, Isoptin);

erythromycin (E-Mycin, Ery-Tab, others), clarithromycin (Biaxin), or telithromycin (Ketek);

an antifungal medication such as itraconazole (Sporanox), fluconazole (Diflucan), or ketoconazole (Nizoral);

drugs that weaken your immune system such as cancer medicine or steroids, cyclosporine (Neoral, Sandimmune, Gengraf), sirolimus (Rapamune), tacrolimus (Prograf), and others;

HIV or AIDS medication such as amprenavir (Agenerase), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), lopinavir-ritonavir (Kaletra), or saquinavir (Invirase, Fortovase).

This list is not complete and there may be other drugs that can interact with simvastatin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?
Your pharmacist can provide more information about simvastatin.

 

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