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Carloc (Carvedilol)
SELECT REF DESCRIPTION MANUFACTURER PACK SIZE STRENGTH OUR PRICE
P1074 Carloc (Carvedilol) Cipla 10 tabs 3.125 mg $2.52
P1075 Carloc (Carvedilol) Cipla 10 tabs 6.25 mg $3.42
P1076 Carloc (Carvedilol) Cipla 10 tabs 12.5 mg $4.95
P1077 Carloc (Carvedilol) Cipla 10 tabs 25 mg $7.65
J382 Carvedilol Generic 10 tabs 3.125 mg $3.66
J383 Carvedilol Generic 10 tabs 6.25 mg $5.05
J82 Coreg (Carvedilol Phosphate) Generic 10 tabs 12.5 mg $6.66
J83 Coreg (Carvedilol Phosphate) Generic 10 tabs 25 mg $4.65
Price is per pack & not per tab.. eg: if pack size is 10 tabs & price is $2.75 then for 100 tabs the price would be $27.50
What is carvedilol?
Carvedilol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Carvedilol is used to treat heart failure and hypertension (high blood pressure). It is also used to treat or prevent heart attack.

Carvedilol may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about carvedilol?
You should not take this medication if you are allergic to carvedilol, or if you have asthma, bronchitis, emphysema, severe liver disease, or a serious heart condition such as heart block, sick sinus syndrome, or slow heart rate (unless you have a pacemaker).

If you need to have any type of surgery, you may need to temporarily stop using carvedilol. Be sure the surgeon knows ahead of time that you are using carvedilol.

Do not stop taking carvedilol without first talking to your doctor. Stopping suddenly may make your condition worse. Carvedilol can cause side effects that may impair your thinking or reactions.

Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol within 2 hours before or after taking extended-release carvedilol (Coreg CR). Also avoid taking medicines or other products that might contain alcohol. Alcohol may cause the carvedilol in Coreg CR to be released too quickly into the body.

Carvedilol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

What should I discuss with my healthcare provider before taking carvedilol?
You should not take this medication if you are allergic to carvedilol, or if you have:

asthma, bronchitis, emphysema;

severe liver disease; or

a serious heart condition such as heart block, sick sinus syndrome, or slow heart rate (unless you have a pacemaker).

Before taking carvedilol, tell your doctor if you have:

diabetes (taking carvedilol can make it harder for you to tell when you have low blood sugar);

low blood pressure;

congestive heart failure;

depression;

kidney disease;

a thyroid disorder;

myasthenia gravis;

pheochromocytoma; or

problems with circulation (such as Raynaud's syndrome).

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. It is not known whether carvedilol is harmful to an unborn baby. Before using this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether carvedilol passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take carvedilol?
Take carvedilol exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor. Follow the directions on your prescription label.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Take this medication with a full glass of water. Take carvedilol at the same time every day. Do not skip doses or stop taking carvedilol without first talking to your doctor. Stopping suddenly may make your condition worse.

You may open the carvedilol extended-release capsule and sprinkle the medicine into a spoonful of applesauce to make swallowing easier. Swallow this mixture right away without chewing. Do not save the mixture for later use. Discard the empty capsule.

If you are switched from carvedilol tablets to carvedilol extended-release capsules (Coreg CR), your daily total dose of this medicine may be higher or lower than before. Older adults may be more likely to become dizzy or feel faint when switching from tablets to extended-release capsules. Follow your doctor's instructions.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. It is important that you not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon that you are using carvedilol. You may need to briefly stop using carvedilol before having surgery.

Carvedilol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

Store carvedilol at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If your next dose is less than 4 hours away, skip the missed dose and take the medicine at the next regularly scheduled time.

Do not take extra medicine to make up the missed dose.

What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, and seizure (convulsions).

What should I avoid while taking carvedilol?
Carvedilol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol within 2 hours before or after taking extended-release carvedilol (Coreg CR). Also avoid taking medicines or other products that might contain alcohol. Alcohol may cause the carvedilol in Coreg CR to be released too quickly into the body. Check the labels of any prescription or over-the-counter medicines you take to see if they contain alcohol (also called ethanol).

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Carvedilol side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

slow or uneven heartbeats;

feeling light-headed, fainting;

feeling short of breath, even with mild exertion;

swelling of your ankles or feet;

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

depression; or

cold feeling in your hands and feet.

Less serious side effects may include:

decreased sex drive, impotence, or difficulty having an orgasm;

sleep problems (insomnia);

tired feeling; or

anxiety, nervousness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Carvedilol Dosing Information
Usual Adult Dose for Angina Pectoris:

Immediate-release tablets:
Initial dose: 6.25 mg orally twice a day with food
Maintenance dose: 6.25 mg to 25 mg orally twice a day with food
Maximum dose: 50 mg per day

Usual Adult Dose for Congestive Heart Failure:

Immediate-release tablets:
Initial dose: 3.125 mg orally twice a day for 2 weeks. If tolerated, increase dosage to 6.25 mg orally twice a day.

Dosage should then be doubled every 2 weeks to the highest level tolerated by the patient.

Maximum dose: 50 mg orally twice a day in patients weighing 85 kg or greater and 25 mg orally twice a day in patients weighing 85 kg or less

Extended-release capsules:
Initial dose: 10 mg orally once a day for 2 weeks. If tolerated, increase dosage to 20 mg, 40 mg, and 80 mg over successive intervals of at least 2 weeks.

Usual Adult Dose for Hypertension:

Immediate-release tablets:
Initial dose: 6.25 mg orally twice a day with food
Maintenance dose: 6.25 mg to 25 mg orally twice a day with food
Maximum dose: 50 mg per day

Extended-release capsules:
Initial dose: 20 mg orally once a day for 7 to 14 days. If tolerated, may increase dosage to 40 mg orally once a day, then again to 80 mg orally once a day after 7 to 14 days.

Maximum dose: 80 mg per day

Usual Adult Dose for Left Ventricular Dysfunction:

Immediate-release tablets:
Initial dose: 6.25 mg orally twice a day (an initial dosage of 3.25 mg twice daily can be given to patients unable to tolerate the initial dosage).

Maintenance dose: If tolerated, the initial dosage may be titrated to 12.5 mg twice a day after 3 to 10 days to a target dose of 25 mg twice a day.

Extended-release capsules:
Initial dose: 20 mg orally once a day (an initial dosage of 10 mg once daily can be given to patients unable to tolerate the initial dosage). If tolerated, may increase dosage to 40 mg after 3 to 10 days, then again to 80 mg orally once a day.

Usual Pediatric Dose for not applicable:

Study (n=46) in children with cardiomyopathy and congenital heart disease:

3 months to 19 years:
Initial: range of 0.03 to 0.21 mg/kg with most patients receiving twice daily dosing.
Maintenance: range of 0.4 mg/kg to 0.75 mg/kg with most patients receiving twice daily dosing.

What other drugs will affect carvedilol?
Before taking carvedilol, tell your doctor if you are using:

allergy treatments (or if you are undergoing allergy skin-testing);

clonidine (Catapres);

cyclosporine (Gengraf, Neoral, Sandimmune);

digoxin (digitalis, Lanoxin);

fluconazole (Diflucan);

guanabenz (Wytensin);

rifampin (Rifadin, Rifater, Rifamate);

insulin or diabetes medication you take by mouth;

an antidepressant such as fluoxetine (Prozac) or paroxetine (Paxil);

a beta blocker such as atenolol (Tenormin), esmolol (Brevibloc), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;

an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);

a heart medication such as amiodarone (Cordarone, Pacerone), quinidine (Quinidex, Quinaglute, Quin-Release), propafenone (Rythmol), nifedipine (Procardia, Adalat), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cartia, Cardizem);

medicine for asthma or other breathing disorders, such as albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), and theophylline (Theo-Dur, Theolair); or

cold medicines, stimulant medicines, or diet pills.

This list is not complete and there may be other drugs not listed that can affect carvedilol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?
Your pharmacist can provide more information about carvedilol.

 

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